Well, Steven Moffat, the show-runner (and de facto Lord President of all things DOCTOR WHO) has finally spoken definitively about the possibility of Amy and Rory Pond (Karen Gillan and Arthur Darvill) returning for the Time Lord’s 50th anniversary story. And his answer is a simple No.
As the creator of Amelia Pond and Rory Williams, Moffat had every right to be their destroyer, and destroy them he did. He both killed them and didn’t kill them the same time by going back to the Weeping Angels’ roots: the Angels sent Amy and Rory into the past and them “live themselves to death.” So they lived full lives and yet died before their time — at the same time. It was the ultimate case of a creator having his cake and eating it too; killing his darlings without murdering them.
So when asked about bringing them back already, Moffat was clear and unambiguous:
“You could never eliminate the possibility of dream sequences and flashbacks, but will the Doctor see them again? No. When I was first talking to Karen and Arthur about it, we said, ‘Let’s make it the proper ending.’ Bringing back things just gives you sequel-itis. Just end it and get out. Heaven knows if they’ll appear in some form of flashback — I have no plans to do that, I have to say — but the story of Amy and The Doctor is definitively over.”
So there you have it, straight from the horse’s mouth: No more Ponds.